Buy 4F-MPH Powder, (also known as4-Fluoromethylphenidate and 4-FMPH) is a stimulant drug that acts as a higher potency dopamine reuptake inhibitor than the closely related methylphenidate.
4-Fluoromethylphenidate was studied further along with other analogues of (±)-threo-methylphenidate (TMP) to assess their potential as anti-cocaine medications. 4F-MPH was reported as having an ED50 mg/kg of 0.26 (0.180.36), regarding its efficacy as a substitute for cocaine, and a relative potency of 3.33 compared to methylphenidate for the same purpose.
Another study found that in the threo-isomers of methylphenidate, the meta and para-substituted compounds with electron-withdrawing substituents tended to have increased binding potency. Compounds containing fluorine, chlorine, bromine and methyl groups were reported to be more potent than methylphenidate. 4F-MPH was reported as having the following values: [3H]WIN 35428 binding of 35.0 ± 3.0 (2) and [3H]dopamine 142 ± 2.0 (2).
4-Fluoromethylphenidate is a Schedule I controlled substance in the US state Alabama. As of 5 May 2017, 4-fluoromethylphenidate is a controlled substance in Canada.
Chemical and physical data
Molar mass: 251.3 g/mol g·mol?1
Important Note DO NOT BUY THIS COMPOUND UNLESS YOU HAVE SCALES CAPABLE OF WEIGHING AS LOW AS 5-10mg ACCURATELY. It seems that the compound is far more active in-vitro than Methylphenidate and even more active than 4-methyl-MPH, so experiments should be planned carefully and accordingly.